Yi-Je Chen Selected Research

TRAM 34

12/2016	The potassium channel KCa3.1 constitutes a pharmacological target for neuroinflammation associated with ischemia/reperfusion stroke.
1/2015	Blood-brain barrier KCa3.1 channels: evidence for a role in brain Na uptake and edema in ischemic stroke.
1/2013	The Ca²⁺-activated K⁺ channel KCa3.1 as a potential new target for the prevention of allograft vasculopathy.
12/2011	The KCa3.1 blocker TRAM-34 reduces infarction and neurological deficit in a rat model of ischemia/reperfusion stroke.

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Yi-Je Chen Research Topics

Disease

5	Stroke (Strokes) 10/2021 - 12/2011
5	Ischemic Stroke 01/2019 - 12/2011
4	Infarction (Infarctions) 01/2018 - 12/2011
3	Brain Edema (Cerebral Edema) 01/2019 - 02/2013
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/2016 - 12/2011
2	Inflammation (Inflammations) 11/2020 - 01/2018
2	Hypoxia (Hypoxemia) 01/2018 - 02/2013
2	Ischemia 12/2016 - 12/2011
2	Edema (Dropsy) 01/2015 - 02/2013
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2021
1	Seizures (Absence Seizure) 01/2020
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2020
1	Hyperglycemia 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2018
1	Neuroinflammatory Diseases 12/2016
1	Pain (Aches) 01/2015
1	Acute Pain 01/2015
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2014
1	Cardiomyopathies (Cardiomyopathy) 03/2014
1	Brain Ischemia (Cerebral Ischemia) 02/2013
1	Hyperplasia 01/2013
1	Fibrosis (Cirrhosis) 01/2013

Drug/Important Bio-Agent (IBA)

4	TRAM 34IBA 12/2016 - 12/2011
2	cariporideIBA 01/2019 - 02/2013
2	Bumetanide (Bumex)FDA LinkGeneric 01/2019 - 02/2013
1	Tobacco Smoke Pollution (Passive Smoking)IBA 01/2021
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2021
1	Purinergic P2X4 ReceptorsIBA 11/2020
1	tetramethylenedisulfotetramine (DSTA)IBA 01/2020
1	PicrotoxinIBA 01/2020
1	RodenticidesIBA 01/2020
1	CME-Carbodiimide (CMEC)IBA 01/2019
1	Streptozocin (Streptozotocin)FDA Link 01/2019
1	Minocycline (Cyclops)FDA LinkGeneric 01/2018
1	Immunologic Factors (Immunomodulators)IBA 01/2018
1	Interleukin-10 (Interleukin 10)IBA 01/2018
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018
1	Nerve Growth Factor (NGF)IBA 01/2018
1	Kv1.3 Potassium ChannelIBA 01/2018
1	Potassium Channels (Potassium Channel)IBA 12/2016
1	Troponin CIBA 01/2016
1	Proteins (Proteins, Gene)FDA Link 01/2015
1	Formaldehyde (Formol)FDA Link 01/2015
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 03/2014
1	Sodium-Hydrogen ExchangersIBA 02/2013
1	Arginine Vasopressin (Argipressin)IBA 02/2013
1	Sodium-Potassium-Chloride SymportersIBA 02/2013
1	CollagenIBA 01/2013
1	Phenobarbital (Luminal)FDA Link 01/2013
1	CalciumIBA 12/2011
1	Eosine Yellowish-(YS) (Eosin)IBA 12/2011
1	Hematoxylin (Haematoxylon)IBA 12/2011

Therapy/Procedure

1	Therapeutics 10/2021
1	Ligation 01/2015
1	Immunotherapy 12/2014
1	Intravenous Administration 02/2013
1	Transplantation 01/2013